“Realizing the Impact of Rotavirus Vaccines”

Day 1 - Monday, 2 August 2010
Opening Session: Moderator - Ciro de Quadros

8:30 – 8:45 | Welcome and Introduction:
Ciro de Quadros
Roger Glass
Shabir Madhi
Umesh Parashar
Duncan Steele
John Wecker

8:45 – 9:00 | Opening Remarks - Roland Edgar Mhlanga

9:00 – 9:20 | A Celebration of rotavirus – Highlights in the Field - ROGER GLASS

9:20 – 9:40 | View from WHO – Global Surveillance, Recommendations and Policies - Mary Agocs

9:40 – 10:10 | Break & Poster Session

Session I: Rotavirus Surveillance and Burden of Disease
Moderator – Mary Agocs

10:10 – 10:25 | Surveillance in Action – Morocco - Mohammed Benhafid

10:25 – 10:40 | Surveillance in Action – Uganda - Andrew Bakainaga

10:40 – 11:15 | Panel Discussion – Lessons Learned, Challenges, Will surveillance address needs with vaccine introduction?
Panel by Mary Agocs, Jason Mwenda and Brendan Flannery

Session II: Update on Rotavirus Vaccines
Moderator – Kathleen Neuzil

11:15 – 11:30 | Monovalent rotavirus vaccine (Rotarix™) - Bernd Benninghoff

11:30 – 11:45 | The Oral Pentavalent Rotavirus Vaccine: A Summary of Safety, Immunogenicity, and Efficacy Clinical Trials and Ongoing Activities - MAX Ciarlet

11:45 – 12:30 | Panel Discussion with Investigators from African and Asian Countries -- Experiences, Lessons Learnt, & New Data
Panel by KATHLEEN NEUZIL and George Armah

12:30 – 13:30 | Lunch

Session III: Impact of Rotavirus Vaccines on Diarrhea Burden
Moderator – Duncan Steele

13:30 – 13:45 | Impact of rotavirus vaccines in the United States - Umesh Parashar

13:45 – 14:00 | Rotavirus vaccines in Australia - Carl Kirkwood

14:00 – 14:15 | How have rotavirus vaccines worked in developing countries in Latin America? - Brendon Flannery

14:00 – 14:30 | Does rotavirus vaccination impact on diarrhoeal mortality? -VESTA RICHARDSON

14:30 – 14:45 | What are the implications of strain replacement after routine introduction of rotavirus vaccines? - Jailson B Correia

14:45 – 15:00 | Natural molecular evolution of rotavirus strains - Jon Gentsch

15:00 – 15:15 | Discussion

15:15 – 15:45 | Coffee break

Session IV: What does the Latest Safety Data show for Rotavirus Vaccines?
Moderator – Umesh Parashar

15:45 – 16:00 | Rotavirus vaccine safety: The United States experience - James Baggs

16:00 – 16:15 | Rotavirus vaccine safety: The Australian experience - Julie Bines

16:15 – 16:30 | Rotavirus in immuno-compromised infants (HIV/SCIDs) - Shabir Madhi

16:30 – 16:50 | WHO View on Rotavirus Vaccine Safety Data - Melinda Wharton

16:50 – 17:30 | Discussion

18:00 Welcome Cocktail Reception and Poster Session

Day 2 – Tuesday, 3 August, 2010

Session V: Rotavirus Vaccine Pipeline
Moderator – Roger Glass

9:00 – 9:15 | The need for a strong vaccine pipeline and mature market for rotavirus - Deborah Atherly

9:15 – 9:30 | What does the rotavirus vaccine pipeline look like? - Georges Thiry

9:30 – 9:45 | Immunogenicity of a neonatal rotavirus vaccine (116E) - Nita Bhandari

9:45 – 10:00 | Can we improve the performance of live oral vaccines? - Steele

10:00 - 10:15 | Should we consider non-live, oral rotavirus vaccines? - Baoming Jiang

10:15 – 10:30 | Discussion

10:30 – 11:00 | Break & Poster Session

Session VI: Late breaking research / Open papers
Moderator – Shabir Madhi

11:00 – 11:15 | Protection conferred by natural rotavirus infection against subsequent infection and disease in an Indian birth cohort - Gagandeep Kang

11:15 – 11:30 | Hospital based rotavirus surveillance among under five children in Ethiopia - Almaz Abebe

11:30 – 11:45 | Safety of the Oral Pentavalent Rotavirus Vaccine in Kenya among HIV-Positive Infants - G NYAMBANE

11:45 – 12:00 | What do decision makers really want? - Tony Nelson

12:00 – 12:15 | Discussion

12:15 – 13:30 | Lunch

Session VII: Next Steps for Rotavirus Vaccine
Moderator – John Wecker

14:00 – 16:00 | Translating Science into Policy: What are the key hurdles to introduction of rotavirus vaccines in developing countries and how can they be overcome? Panel by John Wecker and Deo Nshimirimana

16:00 – 16:30 | Coffee Break

16:00 – 17:30 | Summary - Duncan Steele Summary

16:30 – 17:30 | Call to Action - John Wecker