The Coalition against Typhoid (CaT) is a global forum of health and immunization experts working to expedite and sustain evidence-informed decisions at the global, regional and country levels regarding the use of typhoid vaccination to prevent childhood enteric fever. The Sabin Vaccine Institute serves as the secretariat of the CaT through a three-year grant from the Bill & Melinda Gates Foundation.
Typhoid is a bacterial infection caused by Salmonella Typhi and is transmitted via ingestion of contaminated water or food. The greatest burden of disease is among school and pre-school-aged children living in areas without access to safe water or improved sanitation. The World Health Organization (WHO) estimates there are 16-33 million cases of typhoid each year, causing at least 200,000 deaths. In populations where the basic rights of access to safe water and improved sanitation have yet to be addressed, typhoid vaccination can help to reduce this gap in equity and social justice.
The primary goal of the CaT is to define the barriers for adoption of typhoid vaccine and the key activities needed for the barriers to be overcome.
This goal will be achieved through:
The objectives of the CaT will be accomplished by drawing upon the skills of partners and the institutions they represent. Participation in the coalition membership is open to any institution interested in contributing to the prevention and control of typhoid fever.
Learn more about the launch of the CaT.
Learn more about WHO pre-qualification of typhoid vaccines.
Learn more about typhoid fever.
