Typhoid Research & Advocacy

One-third of the world’s population is at risk of contracting typhoid, a systemic bacterial infection spread through contaminated food and water that kills an estimated 128,000 people each year, primarily children in low-income countries. Caused by the bacteria Salmonella enterica serotype Typhi (S. Typhi), typhoid is an acute illness that is often misdiagnosed because its symptoms – prolonged fever, headache, nausea, constipation, loss of appetite and diarrhea – are so common.

Global Consensus

Working together to shape global health solutions is more important than ever. Sabin seeks to extend the benefits of immunization to everyone by bringing together representatives from across the private and public sectors to identify key challenges facing global immunization and help establish best practices and recommendations to overcome them.

Introduction & Expansion

Over the last decade, many new vaccines have been developed, but the promise of these vaccines is only fulfilled when they are administered around the world. To deliver health to as many people as possible, countries need accurate, high-quality data to ensure their resources are used effectively.

Sabin brings together national government officials, policy makers, immunization specialists, researchers and advocates to supply decision makers with the data and expertise they need to make evidence-based decisions on vaccines.

Overseas travelers can sometimes bring back unwanted souvenirs — with tragic consequences. A localized outbreak of typhoid in Auckland, New Zealand has taken the life of one patient and affected 20 others. Public health authorities believe that a traveler to a typhoid-endemic country may have unknowingly contracted the disease and carried it back into the country.

Public Health Experts Discuss Vaccines, Antibiotic Resistance and Surveillance at Conference on Typhoid and Other Invasive Salmonelloses

KAMPALA, UGANDA – April 4, 2017 – Today, the Sabin Vaccine Institute opened the 10th International Conference on Typhoid and Other Invasive Salmonelloses in Kampala, Uganda. Over the course of the three day conference, more than 300 experts from around the world have gathered to discuss new typhoid-related research, as well as how to turn this evidence into action in the fight against typhoid.
After struggling with outbreaks for more than a year, Zimbabwe is facing yet another deadly wave of typhoid as it begins 2017. Hundreds of cases have been reported across the country over the past three months, the vast majority of which have occurred in Harare, Zimbabwe’s capital city, where the local government struggles to provide clean water and to contain sewage. Because typhoid is spread through contaminated food and water, the lack of these basic services means that typhoid bacteria can easily spread throughout the city. Although there are two vaccines for typhoid on the market, both of which have proven safe and effective, they are not readily available to Zimbabweans, even those that live in high-risk areas.
As 2016 has come to a close, our team at the Coalition against Typhoid would like to take a moment to reflect on this busy year. It was a year that illustrated, more clearly than ever, that typhoid is a continuing and major threat to millions around the world. Over the course of 2016, an estimated 21 million people – most of them children – suffered from typhoid. Of these, 220,000 died of the disease. We saw typhoid outbreaks in Malawi, Fiji, Zimbabwe and other countries. In endemic countries like India and Nepal, the monsoon season worsened the impact of this disease. In 2016, typhoid struck at ordinary places like schools and weddings, and also at the most vulnerable places, such as refugee camps, reminding us that this disease doesn’t discriminate.
Meet Nurunnahar. Like many school-aged children around the world, this Bangladeshi nine-year-old girl thought she would cool off from the heat of the summer with a glass of lemonade.
Despite the many classic symptoms of typhoid, the doctors could not confirm his illness. In Bangladesh, where many medical facilities don’t have the capability for running diagnostic tests, this is not unusual. But unwilling to give up, Samir’s parents then took him to a specialized pediatric hospital.

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