Today marks the first day of vaccinations for Phase I, Part II clinical testing of Sabin's human hookworm vaccine in Brazil.

Congratulations to WIPO Re:Search on its one year anniversary!

PLOS Neglected Tropical Diseases Journal Celebrates Fifth Anniversary by Announcing Geopolitics Collection, Call for Papers, and More

The open-access journal, PLoS NTDs, celebrated its fifth anniversary. To commemorate this great achievement, the journal compiled editorials and research papers published over the last five years to create a collection, called “The Geopolitics of NTDs.”

The collection focuses on the geographic distribution of NTDs by region to highlight the key differences as well as similarities between the diseases in different areas around the world.

Combating Neglected Diseases

October 11, 2012 | Financial Times

The Financial Times special report “Combating Neglected Diseases” contains in-depth stories and interviews featuring several of Sabin’s key programs, including Sabin Vaccine Development, the Global Network for Neglected Tropical Diseases and the Dengue Vaccine Initiative.

Read the full report here.

The Financial Times

DoV Collaboration Leadership commits to making DoV vision a reality

This pledge proclaims the commitment by the Decade of Vaccines Collaboration Leadership Council to make the vision of the Decade of Vaccines a reality through the implementation of the Global Vaccine Action Plan (GVAP). This pledge also shows the DoV Collaboration's commitment to the principles of Every Woman Every Child.
Sabin

About Leishmaniasis

Leishmaniasis includes two major diseases, cutaneous leishmaniasis and visceral leishmaniasis, caused by more than 20 different leishmanial species. Cutaneous leishmaniasis, the most common form of the disease, causes skin ulcers, and is the form upon with the Sabin PDP focuses. Visceral leishmaniasis is more rare, but causes a severe systemic disease that is usually fatal without treatment. Leishmaniasis is transmitted by the bite of  a sand fly. Many leishmanial species infect animals as well as humans.

About Chagas Disease

Today Chagas disease is one of the world’s most important neglected tropical diseases (NTDs) and a leading cause of poverty in Latin America. An estimated 10 million people are infected worldwide with more than 99% of the cases occurring in Latin America, especially in the poorest countries in the region.

Chagas Disease Vaccine

The Sabin PDP is currently engaged in collaboration for early research and development for a bivalent therapeutic vaccine for the treatment of chronic Chagas disease (American trypanosomiasis). It would be the first therapeutic vaccine for this disease. The vaccine is comprised of two Trypanosoma cruzi recombinant proteins formulated on alum. One of the antigens is a unique T. cruzi 24 kDa antigen (Tc24) and the other is a unique T. cruzi surface transialidase (TSA-1).

History

The Schistosomiasis Vaccine Initiative was launched in 2008 through funding from Mr. Morton Hyman and the Blavatnik Family Foundation. In collaboration with researchers at James Cook University and The George Washington University, a promising antigen, Sm-TSP-2, was selected for development.

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