In collaboration with researchers at the James Cook University and The George Washington University, a promising new antigen, Sm-TSP-2 (Schistosoma mansoni Tetraspanin-2), was selected for development as a schistosomiasis vaccine. Then at Texas Children's Hospital and Baylor College of Medicine, Sabin and its partners developed the process for manufacture of the vaccine under cGMP, and was followed by technology transfer to Sabin's manufacturing partner, Aeras. Following final lot release, a toxicology study and subsequent regulatory filing for the vaccine are scheduled to take place in 2013 with a Phase 1 clinical trial slated to begin in late 2013/2014.