Schistosomiasis afflicts over 250 million people around the globe and is the deadliest disease among the seven most prevalent NTDs, killing an estimated 280,000 people annually. Thanks to private donations from Mr. Morton Hyman, Dr. Gary Michelson, Texas Children’s Hospital and the Blavatnik Family Foundation, the Schistosomiasis Vaccine Initiative (SVI) utilizes and leverages the Sabin Vaccine Institute PDP’s existing programmatic and technical infrastructure to produce and evaluate a schistosomiasis vaccine. Major partner organizations of this initiative include Aeras (Maryland), Instituto Butantan (Brazil), Texas Children’s Hospital/Baylor College of Medicine (Houston), George Washington University (DC), University of Kansas (Kansas) and James Cook University (Australia).