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Publications: |
Cancer Vaccines"Lessons from randomized phase III studies with active cancer immunotherapies – Outcomes from the 2006 Meeting of the Cancer Vaccine Consortium (CVC)" published in Vaccine 25:B97-B109 (27 September 2007). "A Clinical Development Paradigm for Cancer Vaccines and Related Biologics" published in Journal of Immunotherapy 30:1-15 (January 2007). This is the report of the Cancer Vaccine Clinical Trial Working Group, a joint initiative of the Cancer Vaccine Consortium and the International Society for Biological Therapy of Cancer. Two papers published in Cancer Immunology Immunotherapy: "Results and harmonization guidelines from two large-scale international Elispot proficiency panels conducted by the Cancer Vaccine Consortium (CVC/SVI)" describes CVC’s ImmunoAssay Proficiency Panel Program, which develops harmonization guidelines for the industry. This program was initiated with an international Elispot proficiency panel comprised of 36 laboratories in 2005, followed by a second panel of 29 participating laboratories in 2006. "Toward the harmonization of immune monitoring in clinical trials: Quo vadis?" is a joint position commentary by the CVC and the C-IMT (Association for Immunotherapy of Cancer, an affiliate of the CVC) supporting the findings of both organizations. The paper calls for harmonization to provide markers for developing new therapies in clinical trials, thus helping improve the clinical success of immunotherapies and bringing them to patients more expeditiously.
The Sabin Colloquium on Cancer Vaccines and Immunotherapy From 1999-2005, the Albert B. Sabin Vaccine Institute's Annual Colloquium on Cancer Vaccines and Immunotherapy brought together 35-50 of the world's foremost cancer vaccine scientists from multiple disciplines for unusually open discussion of ideas and data, much of it so new it was not yet published. By speeding the exchange of information, by taking a fresh look at cancer research paradigms, and by fostering new collaborations among top-level scientists, the Colloquium catalyzed research and development of vaccines to treat and prevent cancer. At these gatherings of leaders in academia, industry, and government, the concept of a Cancer Vaccine Consortium was germinated. For the 2006 and 2007 colloquia, click here. Historic Venues
Leadership The Colloquium on Cancer Vaccines was conceived by Sabin Vaccine Institute Founding Chairman, H.R. "Shep" Shepherd and Robert H. Abplanalp, a close friend of President Nixon and owner of Walker's Cay. The War on Cancer intensified basic biomedical research that produced major insights into how and why cancer cells grow and replicate, and that opened the era of molecular biology. These major scientific advances have enabled scientists to experiment with vaccines that either prevent cancer or train the body's own immune system to attack cancer cells once they occur. Dr. Shepherd and Mr. Abplanalp envisioned the Colloquium as a way to advance the War on Cancer toward several major victories by accelerating development of cancer vaccines. For the first few years, the Colloquium was co-chaired by two distinguished cancer vaccinologists. The inaugural Colloquium, in March 1999, was co-chaired by James P. Allison, Ph.D., Director of Cancer Research Laboratories and Professor of Immunology at the Howard Hughes Medical Institute at the University of California, Berkeley; and Drew Pardoll, M.D., Ph.D., Professor of Oncology at Johns Hopkins University School of Medicine. Starting with the second Colloquium, co-chairs each served for two years. Dissemination of Ideas Also starting with the second Colloquium, a summary report and a more extensive proceedings document were prepared each year. The latter are available for download as follows (Adobe Acrobat® Reader required):
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The first six Colloquia were convened at 
The intimate setting of the Colloquium encouraged informal interaction, creative thinking and relationship building. Some Colloquium participants forged new research collaborations with one another. Many returned to their laboratories excited to investigate new ideas generated at the meeting. 
Proceedings of the Sixth Annual Walker's Cay Colloquium on Cancer Vaccines and Immunotherapy 
Proceedings of the Fifth Annual Walker's Cay Colloquium on Cancer Vaccines and Immunotherapy 
Proceedings of the Fourth Annual Walker's Cay Colloquium on Cancer Vaccines and Immunotherapy 
Proceedings of the Third Annual Walker's Cay Colloquium on Cancer Vaccines and Immunotherapy 
Proceedings of the Second Annual Walker’s Cay Colloquium on Cancer Vaccines and Immunotherapy