One-third of the world’s population is at risk of contracting typhoid, a systemic bacterial infection spread through contaminated food and water that kills an estimated 128,000 people each year, primarily children in low-income countries. Caused by the bacteria Salmonella enterica serotype Typhi (S. Typhi), typhoid is an acute illness that is often misdiagnosed because its symptoms – prolonged fever, headache, nausea, constipation, loss of appetite and diarrhea – are so common.
Vaccine introduction, policy and financing are complex issues, and countries must achieve ambitious immunization targets with limited available resources. To make informed decisions for the health of their people, decision makers need accurate, up-to-date information to identify vulnerable populations, assess burden of disease, evaluate vaccine efficacy and cost-effectiveness, and measure the efficiency of immunization programs.
Over the last decade, many new vaccines have been developed, but the promise of these vaccines is only fulfilled when they are administered around the world. To deliver health to as many people as possible, countries need accurate, high-quality data to ensure their resources are used effectively.
Sabin brings together national government officials, policy makers, immunization specialists, researchers and advocates to supply decision makers with the data and expertise they need to make evidence-based decisions on vaccines.