A new study published in Nature online last week estimates that there are more than three times as many dengue infections as in the official World Health Organization (WHO) figure. The WHO estimates 50-100 million dengue infections a year, while “The global distribution and burden of dengue” report argues that there are 390 million dengue infections per year.
As the prominence of dengue grows, the need for an up-to-date and comprehensive understanding of the burden of disease becomes more and more important. For dengue, this means not just mortality but also morbidity; the true cost of the disease lies not just in the lives lost, but in the burden placed on health systems, the days of work missed, and other harder to calculate figures.
As part of the DVI program, a team has been working to develop and advance a model for the impact of dengue vaccine immunization on infection and disease, one that allows the simulation of a wide range of scenarios, including the impact of vector control.

By Alyah Khan

The tremendous scope of the dengue problem becomes clear when you consider the number of places where the virus is present.

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