Hookworm Gets the Genome Treatment
Peter Hotez, Sabin President, was a contributer in a study that succesfully sequenced the genome of the hookworm.
The genome of the hookworm has been sequenced, paving the way for better remedies against the disease-causing parasite that infects about 700 million people, according to a new study. An international team of researchers identified genes that help the hookworm invade its host, evade the body's immune defences, and feed undisturbed on human blood for up to a decade.
"Our findings provide information on molecules that are essential for the worm's survival, therefore making them potential candidates for development of therapeutics to combat hookworm infections," says study co-author Makedonka Mitreva of the Washington University School of Medicine.