Parasites: Hookworm Vaccine Will Be Tried in Africa
The New York Times highlights Sabin's work on developing the world's first Human Hookworm vaccine.
" Dr. Peter J. Hotez, director of the Sabin Vaccine Institute, explained that the vaccine creates antibodies not against the parasites themselves but against two enzymes found in the worm’s own gut — one that detoxifies the iron in its blood diet, and another that digests blood proteins. Without those enzymes the worm slowly dies.
The trial will start on a few adults in Gabon, and children will eventually be enrolled. Even if all goes well, the trial could take at least five years. But Dr. Hotez noted that he began work on the vaccine as a graduate student at Rockefeller University 30 years ago “and I’ve been working on it my whole life.”