Phase 1 Clinical Trial of Human Hookworm Vaccine Successfully Completed

WASHINGTON, D.C. — September 3, 2014 — The Sabin Vaccine Institute (Sabin) today announced that its product development partnership (Sabin PDP) successfully completed a Phase 1 clinical trial in Brazil of Na-GST-1/Alhydrogel®, a vaccine candidate for human hookworm, one of the most pervasive neglected tropical diseases (NTDs) affecting the world’s poor. The Sabin PDP is based at Sabin Vaccine Institute and Texas Children’s Hospital Center for Vaccine Development at Baylor College of Medicine in Houston, Texas.

Statement by the Sabin Vaccine Institute on the introduction of the “End Neglected Tropical Diseases Act”

On June 11, 2014, Congressman Chris Smith (R-NJ) introduced a bipartisan bill in the House of Representatives to support the control and elimination of neglected tropical diseases (NTDs) in the United States and abroad. H.R. 4847, the “End Neglected Tropical Diseases Act,” calls for the expansion of USAID’s NTD program; increased U.S. Government advocacy for NTDs among international development and financing institutions; reporting from the U.S. Department of Health and Human Services on NTDs in the United States; the creation of one or more NTD centers of excellence to increase research and development (R&D); and the establishment of a panel on intestinal worm infections, one of the most pervasive NTDs.

Statement by the Sabin Vaccine Institute: A rare spotlight for a neglected disease

Schistosomiasis, a parasitic disease transmitted by freshwater snails, infects more than 200 million people worldwide, causing horrific symptoms, especially in girls and women. Schistosomiasis is the second deadliest parasitic disease after malaria, killing an estimated 300,000 people annually, and has been linked as a co-factor in the spread of HIV/AIDS in sub-Saharan Africa and the incidence of bladder cancer.

Sabin Vaccine Institute Hosts 20th Anniversary Scientific Symposium

WASHINGTON, D.C. – April 25, 2014 – Twenty years ago, the immunization landscape was starkly different from what it is now. More than 100,000 cases of poliomyelitis and 1.2 million cases of measles occurred each year, and few low-income countries outside of the Americas had immunization plans. Neglected tropical diseases (NTDs), which have existed since biblical times, wreaked havoc without recognition due to an absence of coordinated advocacy and government funding.

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