Phase 1 Clinical Trial of Human Hookworm Vaccine Successfully Completed

WASHINGTON, D.C. — September 3, 2014 — The Sabin Vaccine Institute (Sabin) today announced that its product development partnership (Sabin PDP) successfully completed a Phase 1 clinical trial in Brazil of Na-GST-1/Alhydrogel®, a vaccine candidate for human hookworm, one of the most pervasive neglected tropical diseases (NTDs) affecting the world’s poor. The Sabin PDP is based at Sabin Vaccine Institute and Texas Children’s Hospital Center for Vaccine Development at Baylor College of Medicine in Houston, Texas.

Statement by the Sabin Vaccine Institute on the introduction of the “End Neglected Tropical Diseases Act”

On June 11, 2014, Congressman Chris Smith (R-NJ) introduced a bipartisan bill in the House of Representatives to support the control and elimination of neglected tropical diseases (NTDs) in the United States and abroad. H.R. 4847, the “End Neglected Tropical Diseases Act,” calls for the expansion of USAID’s NTD program; increased U.S. Government advocacy for NTDs among international development and financing institutions; reporting from the U.S. Department of Health and Human Services on NTDs in the United States; the creation of one or more NTD centers of excellence to increase research and development (R&D); and the establishment of a panel on intestinal worm infections, one of the most pervasive NTDs.

New Global Consortium to Advance First-Ever Clinical Testing of the Human Hookworm Vaccine in Sub-Saharan Africa

AMSTERDAM & WASHINGTON, DC – September 26, 2013 – The HOOKVAC consortium, led by the Academic Medical Center (AMC) at the University of Amsterdam, today announced it has been awarded a grant of six million Euros from the European Commission FP7 programme to expand the Sabin Vaccine Institute Product Development Partnership’s (Sabin PDP) work to develop and test a vaccine for human hookworm, a disease that infects 600-700 million of the world’s poorest people. Under this grant, the HOOKVAC consortium, which includes partners from the European Union, United States and Africa, will begin the first clinical testing of the human hookworm vaccine in the West African nation of Gabon.

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