Phase 1 Clinical Trial of Human Hookworm Vaccine Successfully Completed

WASHINGTON, D.C. — September 3, 2014 — The Sabin Vaccine Institute (Sabin) today announced that its product development partnership (Sabin PDP) successfully completed a Phase 1 clinical trial in Brazil of Na-GST-1/Alhydrogel®, a vaccine candidate for human hookworm, one of the most pervasive neglected tropical diseases (NTDs) affecting the world’s poor. The Sabin PDP is based at Sabin Vaccine Institute and Texas Children’s Hospital Center for Vaccine Development at Baylor College of Medicine in Houston, Texas.

Statement by the Sabin Vaccine Institute on the introduction of the “End Neglected Tropical Diseases Act”

On June 11, 2014, Congressman Chris Smith (R-NJ) introduced a bipartisan bill in the House of Representatives to support the control and elimination of neglected tropical diseases (NTDs) in the United States and abroad. H.R. 4847, the “End Neglected Tropical Diseases Act,” calls for the expansion of USAID’s NTD program; increased U.S. Government advocacy for NTDs among international development and financing institutions; reporting from the U.S. Department of Health and Human Services on NTDs in the United States; the creation of one or more NTD centers of excellence to increase research and development (R&D); and the establishment of a panel on intestinal worm infections, one of the most pervasive NTDs.

Statement by the Sabin Vaccine Institute: A rare spotlight for a neglected disease

Schistosomiasis, a parasitic disease transmitted by freshwater snails, infects more than 200 million people worldwide, causing horrific symptoms, especially in girls and women. Schistosomiasis is the second deadliest parasitic disease after malaria, killing an estimated 300,000 people annually, and has been linked as a co-factor in the spread of HIV/AIDS in sub-Saharan Africa and the incidence of bladder cancer.

Sabin Vaccine Institute Hosts 20th Anniversary Scientific Symposium

WASHINGTON, D.C. – April 25, 2014 – Twenty years ago, the immunization landscape was starkly different from what it is now. More than 100,000 cases of poliomyelitis and 1.2 million cases of measles occurred each year, and few low-income countries outside of the Americas had immunization plans. Neglected tropical diseases (NTDs), which have existed since biblical times, wreaked havoc without recognition due to an absence of coordinated advocacy and government funding.

Indonesia’s Competitiveness at risk from Neglected Diseases of Poverty

WASHINGTON, D.C. – February 27, 2014 – The control and elimination of neglected tropical diseases (NTDs) is one of the most cost-effective ways Indonesia can sustain economic growth and reduce inequality, said scientists today in an analysis published in PLOS Neglected Tropical Diseases. While Indonesia is poised to defeat NTDs by 2020, it has an opportunity to scale up national programs, integrate NTDs with other development efforts, strengthen coordination and enhance collaboration among key partners.

Uncertain budget climate threatens safety of U.S. troops, veterans

WASHINGTON, D.C. – December 26, 2013 – Current budget restrictions and the threat of future cuts jeopardize the safety and mission readiness of U.S. troops, veterans’ health, and capabilities of the U.S. military’s tropical medicine research and development (R&D), said researchers today in an editorial published in PLOS Neglected Tropical Diseases.

New framework for neglected tropical diseases could unlock potential for world’s poorest people

WASHINGTON, D.C. – November 22 – A new concept and policy framework published in PLOS NTDs outlines concrete steps for the global development community as it works to synthesize health goals with economic, environmental and social priorities. The concept, “blue marble health,” emphasizes the role of the Group of 20 (G20) nations in tackling neglected tropical diseases (NTDs) to expedite poverty reduction efforts.

A Leading Cause of Heart Disease Ignored in North America’s Poorest Communities

WASHINGTON, D.C. – October 31, 2013 – A leading cause of heart disease remains overlooked in North America’s most impoverished communities, researchers said today in an editorial published in PLOS Neglected Tropical Diseases. Chagas disease has rendered a heavy health and economic toll, yet insufficient political and medical support for gathering specific data, providing diagnosis and treatment, and developing new tools have impeded much-needed breakthroughs.

Michael Posner Joins Sabin Vaccine Institute’s Board of Trustees

WASHINGTON, DC – October 21, 2013 – The Sabin Vaccine Institute today announced the election to its Board of Trustees of Michael H. Posner, Professor of Business and Society at New York University’s Stern School of Business. For more than three decades, Mr. Posner has advanced the causes of inclusive global human rights, dignity, freedom and justice.

New Global Consortium to Advance First-Ever Clinical Testing of the Human Hookworm Vaccine in Sub-Saharan Africa

AMSTERDAM & WASHINGTON, DC – September 26, 2013 – The HOOKVAC consortium, led by the Academic Medical Center (AMC) at the University of Amsterdam, today announced it has been awarded a grant of six million Euros from the European Commission FP7 programme to expand the Sabin Vaccine Institute Product Development Partnership’s (Sabin PDP) work to develop and test a vaccine for human hookworm, a disease that infects 600-700 million of the world’s poorest people. Under this grant, the HOOKVAC consortium, which includes partners from the European Union, United States and Africa, will begin the first clinical testing of the human hookworm vaccine in the West African nation of Gabon.

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