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From Vaccines to Vaccinations

We improve access to vaccines, enable innovation and expand immunization across the globe.

Sabin Begins Marburg Vaccine Trial in U.S.

The Sabin Vaccine Institute has launched a multi-site Phase 2 clinical trial in the U.S. for its Marburg vaccine candidate in Melbourne, Florida. This trial builds on ongoing Phase 2 testing in Kenya and Uganda, with initial findings from that research expected in the coming months.

Two men carry a box of Sabin Marburg vaccines

Q&A: Behind the Marburg Virus Outbreak in Rwanda

Sabin’s rapid delivery of investigational vaccines during Rwanda’s Marburg outbreak showcased exceptional coordination among all the partners. This Q&A unpacks the timeline, Sabin’s role, the clinical trial, the vaccine candidate, and key lessons for future collaborations.

Local Impact, Global Change

Explore how Sabin’s partners drive impact on the ground. Discover their stories here, and check back for updates on new locations and projects.

Clinical Trials

Confronting Deadly Diseases

Vaccines are our best defense against disease. Yet, we still have lethal diseases that need a vaccine solution urgently. Sabin’s R&D team is tackling two such threats: Sudan ebolavirus and Marburg virus disease. There are no approved vaccines for either of these viruses which have left behind a trail of outbreaks, ending many lives and livelihoods in Africa. Sabin’s vaccines are in Phase 2 clinical trials in Uganda and Kenya.

Making a Case for Vaccines

Safe

Vaccines undergo rigorous testing for safety. Preclinical testing, clinical trials and regulatory approval processes ensure that vaccines are safe and effective before they’re given to children or adults.

Safe-Vaccine
Affordable

Successful, sustainable immunization programs are a staple of health care worldwide. Vaccines are a best buy in global health, with economic and social benefits valued up to 44 times the cost of vaccination.

Affordable
Effective

Childhood vaccines save more than 3 million lives each year and confer long-term immunity for most people. Vaccines have successfully controlled many diseases, ended smallpox, and are closing in on eradicating polio.

Effective
Transformative

Vaccines do not only save lives, they change them. Vaccine-preventable diseases cause school absences, lost wages, birth defects and overburdened health systems. Continuing to develop new vaccines, removing barriers to access, countering misinformation and advocating for vaccine equity are critical to helping all communities realize the full benefits of immunization.

Untapped-Potential

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