As 2016 has come to a close, our team at the Coalition against Typhoid would like to take a moment to reflect on this busy year. It was a year that illustrated, more clearly than ever, that typhoid is a continuing and major threat to millions around the world. Over the course of 2016, an estimated 21 million people – most of them children – suffered from typhoid. Of these, 220,000 died of the disease. We saw typhoid outbreaks in Malawi, Fiji, Zimbabwe and other countries. In endemic countries like India and Nepal, the monsoon season worsened the impact of this disease. In 2016, typhoid struck at ordinary places like schools and weddings, and also at the most vulnerable places, such as refugee camps, reminding us that this disease doesn’t discriminate.