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Generating Evidence

Providing Data-Driven Vaccine Evidence

We provide data that policy makers need to make informed immunization decisions.

Our Objectives

Provide evidence to shape vaccine decision-making

for national and global policy makers

Fund multidisciplinary teams

to design, pilot, and evaluate community-based and social media interventions to improve vaccination uptake

Design and sponsor clinical trials

to evaluate the immunogenicity and safety of lower, fractional doses of vaccines

Critical Cholera Vaccine Research

Sabin partnered with Kenya Medical Research Institute (KEMRI) to optimize the use of the oral cholera vaccine, examining dosing and effective intervals between doses. Funded by the Wellcome Trust, the study aims to inform vaccination strategies that could be beneficial in tackling the global resurgence of cholera as well as acute vaccine shortages.

COVID-19 Vaccine Vials

Dose-Optimizing COVID-19 Vaccine Clinical Trial

Sabin was awarded up to $6.3 million from the Coalition for Epidemic Preparedness Innovations (CEPI) for a clinical trial to evaluate the immunogenicity and safety of lower, fractional doses of registered COVID-19 vaccines used as a booster dose. This dose optimizing trial will allow us to understand if smaller doses of COVID-19 vaccines generate similar immune responses to full doses. It will also provide key information as to whether lower doses may have fewer side effects, potentially increasing vaccine acceptance.

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How do countries decide which vaccines to prioritize?

PriorityVax is a web-based tool to help global decision makers set evidence-based priorities that furthers vaccine equity and transparency.

Learn more about PriorityVax